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Elanco Animal Health announces Health Canada approval of Imrestor

Published on 29 March 2016

On March 18, Elanco Animal Health, a division of Eli Lilly and Company, announced the approval of Imrestor in Canada – the first product of its kind for the dairy industry.

Available only by veterinary prescription, Imrestor is approved by the Veterinary Drugs Directorate of Health Canada for the reduction in the incidence of clinical mastitis in the first 30 days of lactation in periparturient dairy cows and periparturient replacement dairy heifers. It is a protein that helps support the natural function of a dairy cow’s immune system during the critical time around calving, when she is most vulnerable to mastitis.

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“Imrestor is an innovative new approach for reducing clinical mastitis by proactively helping to restore the function of a cow’s immune system,” explained Paul Rapnicki, DVM, MBA, associate technical adviser, Elanco Animal Health.

Pivotal efficacy studies conducted for Health Canada approval showed a 31.9 percent reduction in clinical mastitis incidence in the first 30 days of lactation among cows and heifers that received Imrestor compared with control animals. Mastitis is the most common disease among dairy cows, affecting as many as one in four cows. Clinical mastitis affects each cow’s potential, leading to reduced conception rates, an increased risk for another case of mastitis and lost milk production potential throughout the lactation.

Dairy cows experience immune suppression at calving

Immune suppression at calving can leave cows vulnerable to infection and an increased risk of mastitis. Dairy cows and heifers are in need of protection particularly at calving due to a decline in the function of neutrophils – the primary type of white blood cell that recognizes and destroys harmful bacteria. This product helps restore the function and increase the number of neutrophils at calving, which helps the cow to fight invading bacteria that cause mastitis.

Available in prefilled, single-dose syringes, the product is administered with two injections – one seven days prior to the anticipated date of calving and the other within 24 hours after calving – thus helping to protect the cow against mastitis when she needs it most.

Imrestor does not require a meat or milk withdrawal period. It will be available for purchase in 10-dose pack sizes. The product availability date will be announced at a later time.  PD

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References omitted but are available upon request. Click here to email an editor.

—From Elanco Animal Health news release

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